DARMSTADT, Germany - Wednesday, 28. May 2025

Global Phase 3 MANEUVER study of pimicotinib in tenosynovial giant cell tumor (TGCT) met the primary endpoint, demonstrating objective response rate at week 25 of 54.0% versus 3.2% for placebo (p<0.0001)
MANEUVER met all five key secondary endpoints, with statistically significant and clinically meaningful improvements in pain, stiffness, range of motion, physical function, and decrease in tumor volume
Treatment was well-tolerated, with low incidence of treatment discontinuation and dose reductions
 

Not intended for Canada-, UK- or US-based media

(BUSINESS WIRE) -- Merck, a leading science and technology company, today announced the presentation of detailed positive results from Part 1 of the global Phase 3 MANEUVER trial evaluating pimicotinib, a potentially best-in-class investigational colony stimulating factor-1 receptor (CSF-1R) inhibitor in development by Abbisko Therapeutics Co., L ... Read more »

Hikma Pharmaceuticals PLC (Hikma, Company) is pleased to announce that Fitch has upgraded its long-term issuer default rating and the senior unsecured rating on Hikma Finance USA LLC’s $500 million notes to ‘BBB’ from ‘BBB-‘ with a stable outlook.

Khalid Nabilsi, CFO of Hikma said: “I am pleased that now both Fitch and S&P have upgraded Hikma to BBB, reinforcing our investment grade rating. These upgrades are a strong endorsement of our strategic direction, financial discipline, and operational resilience. They underscore Hikma’s solid market position across key geographies and reflect confidence in our ability to consistently deliver strong financial results, supported by our diversified business model, robust balance sheet, and prudent capital allocation.”

About Hikma

Hikma helps put better health within reach every day for millions of people around the world. For more than 45 ... Read more »

(BUSINESS WIRE) -- The Estée Lauder Companies Inc. (NYSE: EL) today announced the appointment of Lisa Sequino as the new President, Makeup Brand Cluster, responsible for leading the strategic direction and global growth of makeup, and overseeing the company’s portfolio of makeup brands, including M·A·C, Bobbi Brown, Too Faced, Smashbox and GLAMGLOW. Ms. Sequino will report to Jane Hertzmark Hudis, Executive Vice President, Chief Brand Officer and will be effective in the role as of June 9, 2025.

A respected leader with more than two decades of experience in the beauty industry, Ms. Sequino returns to The Estée Lauder Companies with a distinctive blend of deep institutional knowledge and proven success as a CEO. In her new role, she will be responsible for accelerating innovation and makeup trends, step-changing consumer recruitment and enhancing local relevance. Her appointment reflects the company’s continued investment in strengthening its makeup ... Read more »

CODE81, a leading regional technology innovator, announces the signing of a strategic Memorandum of Understanding (MoU) with Commercial Bank of Dubai (CBD). This partnership aims to enhance CBD’s data and analytics capabilities, empowering smarter decision-making and accelerating the bank’s digital transformation journey.

The collaboration addresses one of the most pressing challenges faced by large financial institutions: managing and leveraging complex data assets effectively. Under the MoU, CODE81 will support CBD in overcoming data silos, improving data governance frameworks, and deploying scalable, AI-powered analytics infrastructure aligned with CBD’s business objectives. These efforts will enable more agile, insight-driven operations that drive measurable business outcomes.

Dr Bernd Van Linder, Chief Executive Officer at CBD, commented, "At CBD, we believe technology must ultimately serve and benefit the cus ... Read more »

 (BUSINESS WIRE)--Manhattan Associates Inc. (NASDAQ: MANH), the global leader in supply chain commerce, today announced an expanded go-to-market (GTM) partnership with Google Cloud. All Manhattan Active® solutions are available on Google Cloud Marketplace, enabling customers to accelerate their digital transformation success. Th ... Read more »

ATHENS, Greece - Thursday, 29. May 2025

(BUSINESS WIRE)--This year, Olympia, Greece, the birthplace of the Olympic Games, welcomes the inaugural International Humanoid Olympiad. From August 29th to September 2nd, at the International Olympic Academy in Olympia, humanoid robots will participate in demonstrations and Olympic-inspired games, showcasing their dexterity and intelligence, while global leaders in robotics and AI will share insights through expert talks and workshops. Blending millennia-old values, ethos, and ideals with a bold vision for the future, the event will spotlight how human creativity and robotics are shaping the future.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250528788233/en/

This global gathering brings together state-of-the-art humanoid robots in spectacular showcases designed to captivate audiences of all ages and backgrounds while their creators, researchers, ... Read more »

 WAMD onboards 30% of Kuwait’s banked population in first 3 months; real-time transactions powered by KNET and ACI Worldwide up more than 12x since 2024

(BUSINESS WIRE) -- ACI Worldwide (NASDAQ: ACIW), an original innovator in global payments technology, and  ... Read more »

WILMINGTON, Del. -
Simplifying domain validation to reduce overhead, accelerate certificate issuance, and ensure readiness for industry-wide changes.

(BUSINESS WIRE)--CSC, an enterprise-class domain security provider and world leader in domain management, brand protection, and anti-fraud solutions, today announces the launch of Domain Control Validation as a Service (DCVaaS), a unique offering designed to simplify and expedite secure sockets layer (SSL)/transport layer security (TLS) certificate validation processes for all its CSC Trusted Secure digital certificate clients.

DCVaaS empowers users with a streamlined, centralized solution for domain control validation, eliminating the need for repetitive validations during certificate renewals. It significantly reduces the time and effort required to manage certificate life cycles—making it an essential tool as the industry moves toward shorter certificate validity periods.

This launc ... Read more »

May 26, 2025 03:54 ET| Source: Bitget Limited

Bitget Delivers A Knockout Experience: VIP Access to Karate Combat’s KC54 Dubai UFC Fight

DUBAI, United Arab Emirates, May 26, 2025 (GLOBE NEWSWIRE) -- Bitget, the leading cryptocurrency exchange and Web3 company, brought the heat to Token2049 with an exclusive ringside experience at Karate Combat KC54 in Dubai on May 2nd. Think high-octane strikes, VIP treatment, and a night so wild, even the blockchain felt the impact.

bitget x krtkmbt-38 large

This year, Bitget raised the stakes by offering a premium experience that put crypto enthusiasts right at the heart of the action. Bitget's esteemed VIPs witnessed world-class fighters trade blows while enjoying gourmet food and premium beverages in an exclusive VIP section reserved just for Bitget's key opinion leaders and special guests.

With a crow ... Read more »

(BUSINESS WIRE)--AVEDA, a purpose-driven pioneer of plant-powered, high-performance beauty announces its debut in the U.S. Amazon Premium Beauty store, bringing its assortment of vegan hair, skin, body and lifestyle products to new consumers across the country.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250528898881/en/

“With the launch of AVEDA in the U.S. Amazon Premium Beauty store, we’re not only introducing more people to the world of AVEDA but also highlighting our incredible network of salons,” said Shane Wolf, President AVEDA & Hair Care. “This new online experience gives a glimpse into our world of high performance, vegan hair care for all – from new innovations to iconic classics.”

Amazon customers can shop a wide selection of AVEDA products, including its best-selling franchises Botanical Repair™ for bond building and repair, Invati Ultra ... Read more »