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 – Designation Represents Positive Progress for a Unique Patient Population in Need of Targeted Therapy Options 


CAMBRIDGE, Mass. & OSAKA, Japan-Wednesday 29 April 2020 [ AETOS Wire ]

(BUSINESS WIRE)-- Takeda Pharmaceutical Company Limited (TSE:4502/NYSE:TAK) (“Takeda”) today announced that the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation for its investigational drug mobocertinib (TAK-788) for the treatment of patients with metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations whose disease has progressed on or after platinum-based chemotherapy. There are currently no approved therapies designed to treat this specific form of NSCLC. Mobocertinib is a small-molecule tyrosine kinase inhibitor (TKI) designed to selectively target EGFR and human EGFR 2 (HER2) exon 20 insertion mutations.

The Breakthrough Therapy Designation i ... Read more »

Views: 35 | Added by: africa-live | Date: 04.29.2020 | Comments (0)

BROOKLYN, N.Y.-Saturday 25 April 2020 [ AETOS Wire ]

(BUSINESS WIRE) -- Zymo Research Corp, a California-based life science reagent company and Opentrons Labworks, Inc, makers of affordable and easy-to-use lab robotics, have partnered to create a robust engine for SARS-CoV-2 molecular testing.

As the COVID-19 crisis persists, the need for high-throughput, fast turn-around, and affordable testing platforms will become a matter of vital security to facilitate routine testing for communities around the world. The automated RNA extraction pipeline created with the Opentrons OT-2 liquid handling robot, verified labware, and magnetic module together with Zymo Research’s Quick-DNA/RNA Viral MagBead Kit can serve as the foundation for any lab seeking to perform high-sensitivity SARS-CoV-2 testing.

“The pairing of technologies from Opentrons and Zymo Research establishes a new, automated RNA extraction solution at a time when the legacy suppliers are unabl ... Read more »

Views: 32 | Added by: africa-live | Date: 04.29.2020 | Comments (0)

BOSTON & DUBAI -Tuesday 28 April 2020 [ AETOS Wire ]

(BUSINESS WIRE)-- Berkshire Hathaway Specialty Insurance (BHSI) today announced that it has expanded its Global Property Underwriting Officer team to include Alessandro Cerase, who will focus on General Property, Energy and Construction. Alessandro will also retain his role as Senior Executive Officer (SEO) for BHSI’s Middle East region.

“With our property portfolio growing worldwide, it is the perfect time to expand our global property leadership team, led by Dean LaPierre, and to expand Alessandro’s invaluable contributions to BHSI globally,” said David Fields, Global Chief Underwriting Officer, BHSI. “This move is indicative of the strength and depth of BHSI’s team, not only in property but across all our lines of business -- and of the excellent advancement opportunities available for BHSI teammates around the globe.”

Alessandro joined BHSI as SEO for the Mi ... Read more »

Views: 39 | Added by: africa-live | Date: 04.29.2020 | Comments (0)

COVID-19 impacts results; weighs on outlook

• Orders $7.3 billion, -4%; comparable +1%

• Revenues $6.2 billion, -9%; comparable -7%1

• Income from operations $373 million; margin 6.0%

• Operational EBITA1 $636 million; margin1 10.2%, including 30 basis points stranded costs

• Net income $376 million, -30%

• Basic EPS $0.18, -30%2; operational EPS1 $0.30, -2%

• Cash flow from operating activities -$577 million

 


ZURICH-Tuesday 28 April 2020 [ AETOS Wire ]

(BUSINESS WIRE)-- “The COVID-19 pandemic impacted our first quarter results, lowering revenues and operating margins in all our businesses, although order growth held up well. We are doing our utmost to ensure the health and safety of our employees while maintaining business continuity, serving our customers and continuing to invest in R&D for the long-term,” said Bj√∂rn Rosengren, CEO of ABB. ... Read more »

Views: 38 | Added by: africa-live | Date: 04.29.2020

Maintained its position for the third consecutive year

HANGZHOU, China-Tuesday 28 April 2020 [ AETOS Wire ]

(BUSINESS WIRE)-- Alibaba Cloud, the data intelligence backbone of Alibaba Group, announced that it has the third biggest market share in the global Infrastructure as a Service (IaaS) market and the biggest in the Asia Pacific region for the third year in a row in 2019, said the leading global research and advisory firm Gartner in its latest report.

Alibaba’s market share in the global IaaS market climbed to 9.1% in 2019, up from 7.7% the year earlier, said the firm. The Gartner report, Market Share: IT Services, 2019, also showed that in the Asia Pacific region, Alibaba’s market share increased to 28.2% last year, from 26.1% in 2018.

“We believe our strong growth and leading market position is a testament to the hard work of our teams and the support of our many customers and partners around the world, to whom we are truly gra ... Read more »

Views: 43 | Added by: africa-live | Date: 04.29.2020 | Comments (0)

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